Silver Sulfadiazine Cream 1% is a topical antimicrobial agent formulated to prevent and treat wound infections in patients with second- and third-degree burns. The cream contains micronized silver sulfadiazine, which releases silver ions that exert bactericidal activity against a broad spectrum of gram-positive and gram-negative bacteria, as well as certain yeasts.
Specifications
- 400g jar size
- Silver sulfadiazine 1% w/w (10 mg per gram)
Suitable for
- Patients with second- and third-degree burns to prevent and treat wound infections
Warnings and cautions
Contraindications:
- Hypersensitivity to silver sulfadiazine or any component of the cream
- Pregnant women near term
- Premature infants and newborns under 2 months of age
Precautions:
- Use with caution in patients with impaired hepatic or renal function
- Avoid use in individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency due to risk of hemolysis
- Monitor for signs of systemic absorption, especially when applied to large surface areas
- Potential side effects include transient leukopenia, skin discoloration, burning sensation, and allergic reactions
How to use
- Read the Patient Information Leaflet (if available) before starting treatment and with each refill.
- Ask your doctor or pharmacist if you have any questions.
- This medication is for external skin use only.
- Avoid contact with the eyes unless specifically directed by your doctor.
- A healthcare professional will usually clean and remove dead tissue before application.
- Apply using sterile technique (e.g., wearing sterile gloves and tools).
- Use as directed by your doctor, typically once or twice daily.
- Apply a layer about 1–2 mm (1/16 inch) thick over the wound.
- Ensure the wound is always covered with cream.
- Dressings may be applied, but only if needed.
- If the cream rubs off, reapply immediately.
- Reapply after hydrotherapy or wound cleaning.
- Continue treatment until the wound is healed or ready for skin grafting.
- Use it regularly at the same time(s) each day for best results.
- Inform your doctor if the condition persists or worsens.